"Ontological questions, under this view, are on a par with questions of natural science. Consider the question whether to countenance classes as entities. This, as I have argued elsewhere, is the question whether to quantify with respect to variables which take classes as values. Now Carnap has maintained that this is a question not of matters of fact but of choosing a convenient language form, a convenient conceptual scheme or framework for science. With this I agree, but only on the proviso that the same be conceded regarding scientific hypotheses generally. Carnap has recognized that he is able to preserve a double standard for ontological questions and scientific hypotheses only by assuming an absolute distinction between the analytic and the synthetic; and I need not say again that this is a distinction which I reject. Some issues do, I grant, seem more a question of convenient conceptual scheme and others more a question of brute fact. The issue over there being classes seems more a question of convenient conceptual scheme; the issue over there being centaurs, or brick houses on Elm Street, seems more a question of fact. But I have been urging that this difference is only one of degree, and that it turns upon our vaguely pragmatic inclination to adjust one strand of the fabric of science rather than another in accommodating some particular recalcitrant experience. Conservatism figures in such choices, and so does the quest for simplicity. Carnap, Lewis, and others take a pragmatic stand on the questin of choosing between language forms, scientific frameworks; but their pragmatism leaves off at the imagined boundary between the analytic and the synthetic. In repudiating such a boundary I espouse a more thorough pragmatism. Each man is given a scientific heritage plus a continuing barrage of sensory stimulation; and the considerations which guide him in warping his scientific heritage to fit his continuing sensory promptings are, where rational, pragmatic."
Quine, Willard Van Orman, 1951, Main Trends in Recent Philosophy: Two Dogmas of Empiricism, p. 43.